Personal profile
Biography
Dr Lee Coffey is a Lecturer and Researcher in Molecular Biology with Biopharmaceutical Science at the Department of Science, SETU and is a Principal Investigator at the PMBRC where he is leading the Molecular Biotechnology and Biopharmaceutical Research Group. Lee has attracted over €2 million research funding including Enterprise Ireland and Science Foundation Ireland funding as PI. He is/has supervised fourteen PhD candidates and postdoctoral researchers to date. Lee has led his research through a strong commercial route, authoring 25 publications and numerous inventions, with 5 patents currently pending across multiple territories. Through SETU, Lee has licensed over 1400 biological research technologies to global multi-€B companies. He is the CEO and founder of a spin-out company BIOENZ Technologies Ltd. which has exclusively licensed approx. 4000 biological research technologies and inventions to date.
Lee was awarded the 2022 Established Researcher Category in the SETU Research Excellence Awards, was a National Forum Teaching Hero Award Recipient in 2021 and 2020, has been co-awarded the Technology Ireland Awards 2019 – Outstanding Academic Achievement of the Year and also won the SETU Postgraduate Supervision Excellence Award in 2016.
Research Interests
Lee's research interests include the use of molecular biology techniques to; discover and enhance biopharmaceutical proteins and enhance gene therapy solutions, including gene screening, expression, genome editing, synthetic biology, directed evolution; industrial enzymes for food/feed/pharma/health/industrial applications; biological molecular communications for DNA data storage and biological health monitoring.
Education/Academic qualification
PhD, Molecular Biology
2002 → 2007
Bachelors Degree, BSc Applied Biology with Quality Management
1998 → 2002
External positions
External Examiner, Munster Technological University
2021 → …
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Collaborations and top research areas from the last five years
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Investigation of novel combination therapy for age-related macular degeneration on ARPE-19 cells
Dandamudi, M., McLoughlin, P., Behl, G., Coffey, L., Chauhan, A., Kent, D., Rani, S. & Fitzhenry, L., 19 Apr 2024, In: Frontiers in Drug Delivery. 4, 1337686.Research output: Contribution to journal › Article › peer-review
Open Access -
Transgene Protein Evolution as a Novel Strategy For The Next-Gen Gene Therapy in Canavan Disease. ASGCT 27th Annual Meeting Abstracts (Abstract 252)
Foley, S., Mooney, M., Nyugen, N. B., Lotun, A., Gao, G., Gessler, D. & Coffey, L., 22 Apr 2024, Molecular Therapy. Cell Press, p. p. S1-135 252Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
Open Access -
Recombinant human ASPA expression in E. coli and P. pastoris with activity assay development using ion chromatography
Foley, S., Gao, G., Gessler, D., Ryan, R., Fitzhenry, L. & Coffey, L. V., 31 May 2023, (Unpublished).Research output: Contribution to conference › Poster
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Microfluidic-based Bacterial Molecular Computing on a Chip
Martins, D. P., Barros, M. T., O'Sullivan, B. J., Seymour, I., O'Riordan, A., Coffey, L., Sweeney, J. B. & Balasubramaniam, S., 01 Sep 2022, In: IEEE Sensors Journal. 22, 17, p. 16772-16784 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Using deep learning to detect digitally encoded DNA trigger for Trojan malware in Bio-Cyber attacks
Islam, M. S., Ivanov, S., Awan, H., Drohan, J., Balasubramaniam, S., Coffey, L., Kidambi, S. & Sri-saan, W., 10 Jun 2022, In: Scientific Reports. 12, 1, p. 9631 9631.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus)
Prizes
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ACM NanoCoCoA 2020 Best Paper Award:
Martins, D. P. (Recipient), Quach O'Reilly, H. (Recipient), Coffey, L. V. (Recipient), Cotter, P. (Recipient) & Balasubramaniam, S. (Recipient), 16 Nov 2020
Prize: Honorary award
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Research Excellence Awards Nominee: Established Researcher Category
Coffey, L. V. (Recipient), 2021
Prize: Honorary award
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Winner of the 2019 Outstanding Academic Achievement of the Year
Coffey, L. V. (Recipient), 2019
Prize: Honorary award
Press/Media
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Findings from Waterford Advance Knowledge in Age-Related Macular Degeneration (Investigation of novel combination therapy for age-related macular degeneration on ARPE-19 cells)
Rani, S., Coffey, L. V., Fitzhenry, L., Behl, G. & Dandamudi, M.
02/05/2024
1 item of Media coverage
Press/Media