Personal profile
Biography
Dr Orla O’Donovan obtained a B.Sc. in Biochemistry from NUI, Galway where she also carried out her Ph.D. research on ‘The activating factor for peptidylglycine monooxygenase in bovine pituitary tissue’. On completion of her Ph.D. Orla worked as a clinical biochemist in the Limerick Regional Hospital where her work mainly focused on endocrinology.
In 1998, Orla was appointed to a lectureship in Biochemistry in the South East Technologucal University. She is active in a variety of research areas such as the development of novel pharmaceutical delivery systems/platforms; the identification of the cytokines, adhesion molecules, microparticles and other inflammatory markers that are influenced by cancer; and the mechanism by which metal sequesterisation by seaweeds occurs at a proteomic and genomic level.
Her research activity in SETU has led to awards of over €5.5 million in research funding from competitive national, industrial, EU and international funding. Her collaborations involve clinical, academic and industrial partners in Ireland and internationally.
Education/Academic qualification
PhD, Biochemistry, National University of Ireland, Galway
Award Date: 01 Jul 1997
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 6 Clean Water and Sanitation
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SDG 12 Responsible Consumption and Production
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SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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Artificial Intelligence and the Evolving Landscape of Immunopeptidomics
Vo, T. H., McNeela, E., O'Donovan, O., Rani, S. & Mehta, J. P., 31 Jul 2025, In: Proteomics - Clinical Applications. 19, 6, p. e70018 e70018.Research output: Contribution to journal › Review article › peer-review
Open Access5 Citations (Scopus) -
Building a framework for public and patient involvement in dry eye disease research. A case study
Ames, T., Reynolds, A., Matthews, E., Golestenah, D., Sarfraz, M., Gooney, M., Kinsella, S., Logan, A., Lynch, J., McLoughlin, P., O'Donovan, O., O'Reilly, N., Rani, S., Filipe, H. P., Fitzhenry, L. & Golestaneh, D., Jan 2025, Acta Ophthalmologica. Vol. 103, S284.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Building a framework for public and patient involvement in dry eye disease research. A case study
Ames, T., Reynolds, A. L., Matthews, E., Golestenah, D., Sarfraz, M., Gooney, M., Kinsella, S., Logan, A., Lynch, J., McLoughlin, P., O'Donovan, O., O'Reilly, N., Rani, S., Filipe, H. P. & Fitzhenry, L., 01 Jan 2025, In: Acta Ophthalmologica.Research output: Contribution to journal › Article › peer-review
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Correction: Development and in vitro and ex vivo characterization of a twin nanoparticulate system to enhance ocular absorption and prolong retention of dexamethasone in the eye: from lab to pilot scale optimization. Development and in vitro and ex vivo characterization of a twin nanoparticulate system to enhance ocular absorption and prolong retention of dexamethasone in the eye: from lab to pilot scale optimization (Nanoscale Advances (2025) DOI: 10.1039/d4na01086h)
Sarfraz, M., Behl, G., Rani, S., O'Reilly, N., McLoughlin, P., O'Donovan, O., Reynolds, A. L., Lynch, J. & Fitzhenry, L., 01 Jan 2025, In: Nanoscale Advances. 7, 10, p. 3143Research output: Contribution to journal › Comment/debate
Open Access -
Development and in vitro and ex vivo characterization of a twin nanoparticulate system to enhance ocular absorption and prolong retention of dexamethasone in the eye: from lab to pilot scale optimization
Sarfraz, M., Behl, G., Rani, S., O'Reilly, N., McLoughlin, P., O'Donovan, O., Reynolds, A. L., Lynch, J. & Fitzhenry, L., 23 Apr 2025, In: Nanoscale Advances. 7, 10, p. 3125-3142 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus)
Press/Media
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Department of Science Researcher Focuses on miRNA-Based Therapy (Mechanism of miRNAs and miRNA-mRNA Regulatory Networks in Modulating Drug Resistance in HER2-Positive Breast Cancer: An Integrative Bioinformatics Approach)
Rani, S., Vo, T. H. & O'Donovan, O.
18/12/2024
1 item of Media coverage
Press/Media