A Nitrile-Metabolising Enzyme and a Process for Producing an Acid using Same

Lee V. Coffey; Catherine O'Reilly; Claire Lennon; Erica Owens; Manesiotis Panagiotis; Karen Tambling; Tracey Coady

A Nitrile-Metabolising Enzyme and a Process for Producing an Acid using Same

Lee V. Coffey (Inventor), Catherine O'Reilly (Inventor), Claire Lennon (Inventor), Erica Owens (Inventor), Manesiotis Panagiotis (Inventor), Karen Tambling (Inventor), Tracey Coady (Inventor)

Research output: Patent

Abstract

The present invention relates to an isolated nucleotide sequence andcorresponding polypeptide derived from the niotrile-metabolising Pantoea strain deposited under NCIMB 41853. Saidisolated polypeptide actsas a nitrilase and the invention exends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

Original language	English (Ireland)
Patent number	PCT/EP2012/063315
IPC	C12N 9/78 (2006.1),C12P 7/40 (2006.01)
Priority date	07/07/2011
Filing date	06/07/2012
Publication status	Published - 10 Jan 2013

Keywords

Enzyme
Acid
nucleotide sequence
Polypepide

Cite this

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title = "A Nitrile-Metabolising Enzyme and a Process for Producing an Acid using Same",

abstract = "The present invention relates to an isolated nucleotide sequence andcorresponding polypeptide derived from the niotrile-metabolising Pantoea strain deposited under NCIMB 41853. Saidisolated polypeptide actsas a nitrilase and the invention exends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.",

keywords = "Enzyme, Acid, nucleotide sequence, Polypepide",

author = "Coffey, {Lee V.} and Catherine O'Reilly and Claire Lennon and Erica Owens and Manesiotis Panagiotis and Karen Tambling and Tracey Coady",

year = "2013",

month = jan,

day = "10",

language = "English (Ireland)",

type = "Patent",

note = "PCT/EP2012/063315; C12N 9/78 (2006.1),C12P 7/40 (2006.01)",

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TY - PAT

T1 - A Nitrile-Metabolising Enzyme and a Process for Producing an Acid using Same

AU - Coffey, Lee V.

AU - O'Reilly, Catherine

AU - Lennon, Claire

AU - Owens, Erica

AU - Panagiotis, Manesiotis

AU - Tambling, Karen

AU - Coady, Tracey

PY - 2013/1/10

Y1 - 2013/1/10

N2 - The present invention relates to an isolated nucleotide sequence andcorresponding polypeptide derived from the niotrile-metabolising Pantoea strain deposited under NCIMB 41853. Saidisolated polypeptide actsas a nitrilase and the invention exends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

AB - The present invention relates to an isolated nucleotide sequence andcorresponding polypeptide derived from the niotrile-metabolising Pantoea strain deposited under NCIMB 41853. Saidisolated polypeptide actsas a nitrilase and the invention exends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

KW - Enzyme

KW - Acid

KW - nucleotide sequence

KW - Polypepide

M3 - Patent

M1 - PCT/EP2012/063315

Y2 - 2012/07/06

ER -

A Nitrile-Metabolising Enzyme and a Process for Producing an Acid using Same

Abstract

Keywords

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